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Significance of Proteinuria for Potential IgAN

How do clinicians determine the significance of proteinuria when assessing a patient for potential IgA nephropathy? (IgAN)?

What levels or patterns of proteinuria typically prompt further investigation?

What, if any, specific diagnostic red flags in proteinuria patterns suggest IgAN over other kidney disorders?

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Peer Exchange

HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.

Advancing IgAN Care: Exploring the Next Wave of Treatments

Clinicians assess proteinuria significance in potential IgA nephropathy (IgAN) by evaluating the quantity and persistence of proteinuria, often using a 24-hour urine collection or spot urine protein-to-creatinine ratio. Proteinuria levels exceeding 1g/day typically warrant further investigation. Persistent proteinuria, especially in conjunction with hematuria, raises suspicion for IgAN. Diagnostic red flags include episodic macroscopic hematuria following upper respiratory infections and sustained microscopic hematuria with proteinuria. These patterns, alongside clinical history and laboratory findings, guide the differentiation of IgAN from other kidney disorders.

Panelists discuss how clinicians determine the significance of proteinuria in assessing patients for potential IgA nephropathy (IgAN), including the levels and patterns that prompt further investigation and the specific diagnostic red flags that may suggest IgAN over other kidney disorders.

Proteinuria Variability and IgAN Diagnosis

Overview of IgAN and Its Common Symptoms

IgAN Progression