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Genetic Screening for IgAN

Up to 15% of IgA nephropathy (IgAN) cases are considered familial, should. Should family members of individuals with IgAN be screened or monitored for signs of the disease? If yes, how often?

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Peer Exchange

HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.

Advancing IgAN Care: Exploring the Next Wave of Treatments

Familial IgA nephropathy (IgAN) accounts for up to 15% of cases, raising questions about the need for screening among family members. While there is no consensus on routine screening, some experts suggest monitoring first-degree relatives, especially if they exhibit symptoms or have a family history of kidney disease. The frequency of monitoring is not standardized, but periodic assessments may be beneficial. Genetic counseling could also be considered to evaluate the risk and guide family members on potential preventive measures and lifestyle modifications.

Panelists discuss the importance of screening and monitoring family members of individuals with IgA nephropathy, noting that up to 15% of cases are familial and outlining recommendations for the frequency of such assessments.