First AD

Second AD

Emerging Therapies: a look at the current data: ALIGN

), atrasentan demonstrated a 36% relative reduction in proteinuria with placebo after 36 weeks of treatment. What other data points would be relevant for clinicians?

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Peer Exchange

HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.

Advancing IgAN Care: Exploring the Next Wave of Treatments

Biomarkers and clinical indicators play a crucial role in predicting disease outcomes, offering insights into disease progression, treatment response, and patient prognosis. These indicators can be genetic, molecular, or cellular, and are often identified through advanced diagnostic techniques. For instance, specific gene mutations or protein expressions can indicate the likelihood of disease recurrence or metastasis. Additionally, clinical indicators such as tumor size, stage, and patient health status are integral in assessing outcomes. Personalized medicine leverages these biomarkers to tailor treatment plans, enhancing therapeutic efficacy and patient survival rates.

Panelists discuss how the ALIGN trial data inform the development and potential impact of emerging therapies for IgA nephropathy, particularly focusing on their efficacy in reducing proteinuria and addressing disease pathology.

Overview of IgAN and Its Common Symptoms

IgAN Progression

IgAN vs Other Glomerular Diseases

Biomarkers for IgAN

Genetic Screening for IgAN

Impact of IgAN on Quality of Life

Misdiagnosis and Barriers to Early Detection of IgAN

Differential Diagnoses of IgAN

Significance of Proteinuria for Potential IgAN

Proteinuria Variability and IgAN Diagnosis

Biomarkers and Improving IgAN Diagnostic Accuracy

Primary Treatment Goals for Patients With IgAN

Proteinuria Reduction in Long-Term Kidney Damage Prevention

Symptoms Management and Targeting the Root Cause of IgAN

Unmet Needs in Current IgAN Treatment

Prospective Improvements of Existing IgAN Therapies

Safety of IgAN Treatments

The Promise of Emerging IgAN Therapies

Emerging Therapies: a look at the current data: APPLAUSE