First AD

Second AD

Panelists discuss the pathophysiology of alopecia areata, including the risk factors for disease onset and progression, as well as the role of Janus kinase (JAK) in the disease’s mechanisms.

The Pathophysiology of Alopecia Areata

Video content above is prompted by the following:

Please describe the pathophysiology of alopecia areata. 

    a. What are the risk factors for disease onset and progression? 

    b. What is the role of JAK in the pathophysiology of the disease?

Recent Advances in the Treatment of Alopecia Areata

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Recent Advances in Treatment of Alopecia Areata

HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.

Peer Exchange

Alopecia areata is an autoimmune condition characterized by non-scarring hair loss, where the immune system mistakenly targets hair follicles. Genetic predisposition, environmental factors, and stress are key risk factors for disease onset and progression. The Janus kinase (JAK) pathway plays a crucial role in the pathophysiology of alopecia areata. Dysregulation of this pathway leads to an inflammatory response that contributes to hair follicle destruction. JAK inhibitors have emerged as a promising therapeutic approach, targeting the underlying immune mechanisms and potentially reversing hair loss.

Impact of Alopecia Areata on Quality of Life, and Current Standard of Treatment