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Rheumatology

Rheumatology condition center page is a comprehensive resource for clinical news and insights on rheumatologic disease. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for arthritis, gout, nr-AxSpA, and more.

However, gout flare states of patient acceptable symptom state, low disease activity, or not achieving either were not associated with EQ-5D-3L or HAQ.

Gout Flare State Definitions Help Describe Disease Burden

Less than half of rheumatologists self-reported adhering to febuxostat and allopurinol dosing recommendations. 

Adherence Low for ULT Dosing ACR Gout Guidelines 

The exploratory MIRROR trial found pegloticase with methotrexate improved clinical assessment and quality of life outcomes in uncontrolled gout.

Pegloticase Alongside Methotrexate Improves Uncontrolled Gout in MIRROR Trial

A study found the association between sedentary behavior and gout remained strong even when adjusting for physical activity.

Sedentary Behavior Linked to Increased Gout Risk Even Without Hyperuricemia

These findings, from an observational study, should be confirmed in a randomized, controlled trial.

Colchicine Prophylaxis for Gout Flares Linked to Lower Cardiovascular Events

Troum discussed the AGILE study and how DECT scanning helped visualize improvements in uncontrolled gout.

Orrin Troum, MD: Accurately Imaging Gout With DECT Scanning

CDC, NIH, and AMA recommend PEMs to be at a 6th-to-8th-grade reading level, while assessed materials were readable at high school or higher levels.

Patient Education Materials for Rheumatology, Internal Medicine Don’t Meet Readability Standards

At the highest dose levels, mean plasma urate levels remained below 6.0 mg/dL for up to 12 weeks.

PEGylated Uricase Well-Tolerated, Demonstrates Dose-Dependent Urate-Lowering

Lowering serum urate level to less than 6 mg/dL was not linked to an elevated risk of severe or end-stage kidney disease progression in patients with gout.

Urate-Lowering Therapy Remains Tolerable in Patients with Gout, CKD

Clinically meaningful increases in patient-reported outcomes were identified after 3 doses of SEL-212 and strengthened after 3 additional doses.

SEL-212 Advances Refractory Gout Outcomes with Prolonged Treatment

On the HCPLive gout page, resources on the topics of medical news and expert insight into gouty arthritis can be found. Content includes articles, interviews, videos, podcasts, and breaking news on gout, and more.